CAS 1393-48-2 Thiostrepton from Streptomyces azureus - Analytical Products / Alfa Chemistry

CAT	AP1393482
CAS	1393-48-2
Structure
MDL Number	MFCD00135828
Molecular Weight	1664.89
EC Number	215-734-9
InChI Key	NSFFHOGKXHRQEW-BXVAPQLOSA-N

Description	≥90% (HPLC)
Solubility	acetic acid: soluble 25 mg/mL, clear to hazy, yellow to brownish-yellow; Gram-positive bacteria; parasites
Assay	≥90% (HPLC)
Size	1G
Storage Conditions	−20°C

1

Draft Genome Sequence of Thiostrepton-Producing Streptomyces Azureus ATCC 14921

Kengo Sakihara, Jumpei Maeda, Kosuke Tashiro, Yasuhiro Fujino, Satoru Kuhara, Toshihisa Ohshima, Seiya Ogata, Katsumi Doi

Genome Announc. 2015 Oct 22;3(5):e01183-15.

PMID: 26494661

1

Mechanism of Resistance to Thiostrepton in the Producing-Organism Streptomyces Azureus

E Cundliffe

Nature. 1978 Apr 27;272(5656):792-5.

PMID: 643068

1

Overexpression of the Thiostrepton-Resistance Gene From Streptomyces Azureus in Escherichia Coli and Characterization of Recognition Sites of the 23S rRNA A1067 2'-methyltransferase in the Guanosine Triphosphatase Center of 23S Ribosomal RNA

A Bechthold, H G Floss

Eur J Biochem. 1994 Sep 1;224(2):431-7.

PMID: 7925357

1

Tandem Promoters, tsrp1 and tsrp2, Direct Transcription of the Thiostrepton Resistance Gene (Tsr) of Streptomyces Azureus: Transcriptional Initiation From tsrp2 Occurs After Deletion of the -35 Region

G R Janssen, M J Bibb

Mol Gen Genet. 1990 May;221(3):339-46.

PMID: 2381416

1

Thiostrepton Hijacks Pyoverdine Receptors To Inhibit Growth of Pseudomonas Aeruginosa

Michael R M Ranieri, Derek C K Chan, Luke N Yaeger, Madeleine Rudolph, Sawyer Karabelas-Pittman, Hamdi Abdo, Jessica Chee, Hanjeong Harvey, Uyen Nguyen, Lori L Burrows

Antimicrob Agents Chemother. 2019 Aug 23;63(9):e00472-19.

PMID: 31262758

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