TIMP1 human - Analytical Products / Alfa Chemistry

CAT

IAR4241310

Description	recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
Assay	≥95% (SDS-PAGE)
Form	lyophilized; observed mol wt 28-32 kDa by SDS-PAGE (DTT-reduced.)
Impurity Content	<1 EU/μg endotoxin (LAL test)
Size	10UG
Storage Conditions	−20°C

1

Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer

Zenobia D'Costa, Keaton Jones, Abul Azad, Ruud van Stiphout, Su Y Lim, Ana L Gomes, Paul Kinchesh, Sean C Smart, W Gillies McKenna, Francesca M Buffa, Owen J Sansom, Ruth J Muschel, Eric O'Neill, Emmanouil Fokas

Cancer Res. 2017 Nov 1;77(21):5952-5962.

PMID: 28765154

1

Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver

Barbara Grünwald, Veronika Harant, Susanne Schaten, Monika Frühschütz, Ria Spallek, Bastian Höchst, Katharina Stutzer, Sonja Berchtold, Mert Erkan, Olga Prokopchuk, Marc Martignoni, Irene Esposito, Mathias Heikenwalder, etc.

Gastroenterology. 2016 Nov;151(5):1011-1024.e7.

PMID: 27506299

1

TIMP1 Is a Prognostic Marker for the Progression and Metastasis of Colon Cancer Through FAK-PI3K/AKT and MAPK Pathway

Guohe Song, Shifeng Xu, Hong Zhang, Yupeng Wang, Chao Xiao, Tao Jiang, Leilei Wu, Tao Zhang, Xing Sun, Lin Zhong, Chongzhi Zhou, Zhaowen Wang, Zhihai Peng, Jian Chen, Xiaoliang Wang

J Exp Clin Cancer Res. 2016 Sep 20;35(1):148.

PMID: 27644693

1

Tissue Inhibitor of Matrix Metalloproteinase-1 Promotes Myocardial Fibrosis by Mediating CD63-Integrin β1 Interaction

Abhijit Takawale, Pu Zhang, Vaibhav B Patel, Xiuhua Wang, Gavin Oudit, Zamaneh Kassiri

Hypertension. 2017 Jun;69(6):1092-1103.

PMID: 28373589

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