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TNP-470

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For Research Use Only | Not For Clinical Use
CATIAR4241995
MDL NumberMFCD00870281
Molecular Weight401.88
InChI KeyMSHZHSPISPJWHW-PVDLLORBSA-N
Description≥98% (HPLC)
SolubilityDMSO: >15 mg/mL
Assay≥98% (HPLC)
Formsolid
Size5MG, 25MG
Storage Conditions−20°C
1

Blocking of Methionine aminopeptidase-2 by TNP-470 Induces Apoptosis and Increases Chemosensitivity of Cholangiocarcinoma

Sonexai Kidoikhammouan, Wunchana Seubwai, Atit Silsirivanit, Sopit Wongkham, Kanlayanee Sawanyawisuth, Chaisiri Wongkham

J Cancer Res Ther. Jan-Mar 2019;15(1):148-152.

PMID: 30880771

1

Inhibitory Effects of TNP-470 in Combination With BCNU on Tumor Growth of Human Glioblastoma Xenografts

Dongxiao Yao, Hongyang Zhao, Fangcheng Zhang, Jian Chen, Xiaobing Jiang, Xianli Zhu

J Huazhong Univ Sci Technolog Med Sci. 2010 Dec;30(6):757-61.

PMID: 21181367

1

TNP-470 Promotes Initial Vascular Sprouting in Xenograft Tumors

Jianzhong Huang, Jason S Frischer, Tamara New, Eugene S Kim, Anna Serur, Alice Lee, Angela Kadenhe-Chiwishe, Daniel A Pollyea, Akiko Yokoi, Jocelyn Holash, George D Yancopoulos, Jessica J Kandel, Darrell J Yamashiro

Mol Cancer Ther. 2004 Mar;3(3):335-43.

PMID: 15026554

1

TNP-470 Skews DC Differentiation to Th1-stimulatory Phenotypes and Can Serve as a Novel Adjuvant in a Cancer Vaccine

Derek Hoi-Hang Ho, Roger Hoi-Fung Wong

Blood Adv. 2018 Jul 24;2(14):1664-1679.

PMID: 30012585

1

TNP-470, a Methionine aminopeptidase-2 Inhibitor, Inhibits Cell Proliferation, Migration and Invasion of Human Cholangiocarcinoma Cells in Vitro

Sonexai Kidoikhammouan, Wunchana Seubwai, Nattawat Tantapotinan, Atit Silsirivanit, Sopit Wongkham, Kanlayanee Sawanyawisuth, Chaisiri Wongkham

Asian Pac J Cancer Prev. 2012;13 Suppl:155-60.

PMID: 23480758

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