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TR100

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For Research Use Only | Not For Clinical Use
CATAP1128165865
CAS1128165-86-5
Molecular Weight422.61
InChI KeyXXRLIGWROLDOLS-QOCHGBHMSA-N
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells

Justine R Stehn, Nikolas K Haass, Teresa Bonello, Melissa Desouza, Gregg Kottyan, Herbert Treutlein, Jun Zeng, Paula R B B Nascimento, Vanessa B Sequeira, Tanya L Butler, Munif Allanson, Thomas Fath, Timothy A Hill, etc.

Cancer Res. 2013 Aug 15;73(16):5169-82.

PMID: 23946473

1

A Small Molecule Inhibitor of Tropomyosin Dissociates Actin Binding From Tropomyosin-Directed Regulation of Actin Dynamics

Teresa T Bonello, Miro Janco, Jeff Hook, Alex Byun, Mark Appaduray, Irina Dedova, Sarah Hitchcock-DeGregori, Edna C Hardeman, Justine R Stehn, Till Böcking, Peter W Gunning

Sci Rep. 2016 Jan 25;6:19816.

PMID: 26804624

1

Identification of Cancer-Targeted Tropomyosin Inhibitors and Their Synergy With Microtubule Drugs

Mark A Currier, Justine R Stehn, Ashleigh Swain, Duo Chen, Jeff Hook, Eleanor Eiffe, Andrew Heaton, David Brown, Brooke A Nartker, David W Eaves, Nina Kloss, Herbert Treutlein, Jun Zeng, Irina B Alieva, etc.

Mol Cancer Ther. 2017 Aug;16(8):1555-1565.

PMID: 28522589

1

On-target Action of Anti-Tropomyosin Drugs Regulates Glucose Metabolism

Anthony J Kee, Jayshan Chagan, Jeng Yie Chan, Nicole S Bryce, Christine A Lucas, Jun Zeng, Jeff Hook, Herbert Treutlein, D Ross Laybutt, Justine R Stehn, Peter W Gunning, Edna C Hardeman

Sci Rep. 2018 Mar 15;8(1):4604.

PMID: 29545590

1

Tropomyosin 3.1 Association With Actin Stress Fibers Is Required for Lens Epithelial to Mesenchymal Transition

Justin Parreno, Michael B Amadeo, Elizabeth H Kwon, Velia M Fowler

Invest Ophthalmol Vis Sci. 2020 Jun 3;61(6):2.

PMID: 32492110

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