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Tubacin

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For Research Use Only | Not For Clinical Use
CATAP537049404
CAS537049-40-4
MDL NumberMFCD18452824
Molecular Weight721.86
InChI KeyBHUZLJOUHMBZQY-YXQOSMAKSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥10 mg/mL
Assay≥98% (HPLC)
Colorwhite to tan
Formpowder
Size1MG, 5MG
Storage Conditions−20°C
1

Acetylation Site Specificities of Lysine Deacetylase Inhibitors in Human Cells

Christian Schölz, Brian T Weinert, Sebastian A Wagner, Petra Beli, Yasuyuki Miyake, Jun Qi, Lars J Jensen, Werner Streicher, Anna R McCarthy, Nicholas J Westwood, Sonia Lain, Jürgen Cox, Patrick Matthias, etc.

Nat Biotechnol. 2015 Apr;33(4):415-23.

PMID: 25751058

1

Involvement of HDAC6 in Ischaemia and Reperfusion-Induced Rat Retinal Injury

Haihong Yuan, Hui Li, Ping Yu, Qichen Fan, Xuan Zhang, Wei Huang, Junyi Shen, Yongyao Cui, Wei Zhou

BMC Ophthalmol. 2018 Nov 20;18(1):300.

PMID: 30453928

1

Mechanical Loading Inhibits Cartilage Inflammatory Signalling via an HDAC6 and IFT-dependent Mechanism Regulating Primary Cilia Elongation

S Fu, C L Thompson, A Ali, W Wang, J P Chapple, H M Mitchison, P L Beales, A K T Wann, M M Knight

Osteoarthritis Cartilage. 2019 Jul;27(7):1064-1074.

PMID: 30922983

1

The Histone deacetylase-6 Inhibitor Tubacin Directly Inhibits De Novo Sphingolipid Biosynthesis as an Off-Target Effect

Deanna Siow, Binks Wattenberg

Biochem Biophys Res Commun. 2014 Jul 4;449(3):268-71.

PMID: 24835950

1

Tubacin, an HDAC6 Selective Inhibitor, Reduces the Replication of the Japanese Encephalitis Virus via the Decrease of Viral RNA Synthesis

Chien-Yi Lu, Yi-Chih Chang, Chun-Hung Hua, Chieh Chuang, Su-Hua Huang, Szu-Hao Kung, Mann-Jen Hour, Cheng-Wen Lin

Int J Mol Sci. 2017 May 1;18(5):954.

PMID: 28468311

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