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TWS119

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For Research Use Only | Not For Clinical Use
CATAP601514196-B
CAS601514-19-6
Structure
MDL NumberMFCD09037535
Molecular Weight318.33
InChI KeyVPVLEBIVXZSOMQ-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG
Storage Conditions2-8°C
1

Effects of Glycogen Synthase Kinase-3β Inhibitor TWS119 on Proliferation and Cytokine Production of TILs From Human Lung Cancer

Ying Ying Tang, Si Yuan Sheng, Chuan Gang Lu, Yu Qing Zhang, Jian Yong Zou, Yi Yan Lei, Yong Gu, Hai Hong

J Immunother. 2018 Sep;41(7):319-328.

PMID: 29877972

1

Generation of Clinical-Grade CD19-specific CAR-modified CD8+ Memory Stem Cells for the Treatment of Human B-cell Malignancies

Marianna Sabatino, Jinhui Hu, Michele Sommariva, Sanjivan Gautam, Vicki Fellowes, James D Hocker, Sean Dougherty, Haiying Qin, Christopher A Klebanoff, Terry J Fry, Ronald E Gress, James N Kochenderfer, etc.

Blood. 2016 Jul 28;128(4):519-28.

PMID: 27226436

1

GSK3β Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cell Properties in Triple-Negative Breast Cancer

Geraldine Vidhya Vijay, Na Zhao, Petra Den Hollander, Mike J Toneff, Robiya Joseph, Mika Pietila, Joseph H Taube, Tapasree R Sarkar, Esmeralda Ramirez-Pena, Steven J Werden, Maryam Shariati, Ruli Gao, Mary Sobieski, etc.

Breast Cancer Res. 2019 Mar 7;21(1):37.

PMID: 30845991

1

The PI3K/Akt/GSK-3β/ROS/eIF2B Pathway Promotes Breast Cancer Growth and Metastasis via Suppression of NK Cell Cytotoxicity and Tumor Cell Susceptibility

Fengjiao Jin, Zhaozhen Wu, Xiao Hu, Jiahui Zhang, Zihe Gao, Xiao Han, Junfang Qin, Chen Li, Yue Wang

Cancer Biol Med. 2019 Feb;16(1):38-54.

PMID: 31119045

1

Wnt Canonical Pathway Activator TWS119 Drives Microglial Anti-Inflammatory Activation and Facilitates Neurological Recovery Following Experimental Stroke

Degang Song, Xiangjian Zhang, Junmin Chen, Xiaoxia Liu, Jing Xue, Lan Zhang, Xifa Lan

J Neuroinflammation. 2019 Dec 6;16(1):256.

PMID: 31810470

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