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Tyrphostin AG 490

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For Research Use Only | Not For Clinical Use
CATAP133550308-B
CAS133550-30-8
Structure
MDL NumberMFCD00236452
Molecular Weight294.30
InChI KeyTUCIOBMMDDOEMM-RIYZIHGNSA-N
Descriptionsolid
SolubilityDMSO: soluble 10 mg/ml, clear, yellow; ethanol: 5 mg/mL; H2O: insoluble
Coloryellow
Formsolid
Size5MG, 25MG
Storage Conditions−20°C
1

Blockade of JAK2 by Tyrphostin AG-490 Inhibits Antigen-Induced Eosinophil Recruitment Into the Mouse Airways

K Kumano, A Nakao, H Nakajima, S Miike, K Kurasawa, Y Saito, I Iwamoto

Biochem Biophys Res Commun. 2000 Apr 2;270(1):209-14.

PMID: 10733929

1

Inhibition of Janus Kinases by Tyrosine Phosphorylation Inhibitor, Tyrphostin AG-490

Sajid Rashid, Nousheen Bibi, Zahida Parveen, Shagufta Shafique

J Biomol Struct Dyn. 2015;33(11):2368-79.

PMID: 26017266

1

Inhibition of Zymosan-Induced Kidney Dysfunction by Tyrphostin AG-490

Petya Dimitrova, Valeriya Gyurkovska, Irina Shalova, Luciano Saso, Nina Ivanovska

J Inflamm (Lond). 2009 May 5;6:13.

PMID: 19416544

1

JAK3, STAT, and MAPK Signaling Pathways as Novel Molecular Targets for the Tyrphostin AG-490 Regulation of IL-2-mediated T Cell Response

L H Wang, R A Kirken, R A Erwin, C R Yu, W L Farrar

J Immunol. 1999 Apr 1;162(7):3897-904.

PMID: 10201908

1

Tyrphostin AG-490 Inhibited the Acute Phase of Zymosan-Induced Inflammation

Petya Dimitrova, Nina Ivanovska

Int Immunopharmacol. 2008 Nov;8(11):1567-77.

PMID: 18656556

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