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UBE3A active human

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For Research Use Only | Not For Clinical Use
CATIAR42415048
Descriptionrecombinant, expressed in baculovirus infected Sf9 cells, ≥72% (SDS-PAGE)
Assay≥72% (SDS-PAGE)
Formaqueous solution
Size20μG
Storage Conditions−70°C
1

Analysis of Ubiquitin Recognition by the HECT Ligase E6AP Provides Insight Into Its Linkage Specificity

Lena K Ries, Bodo Sander, Kirandeep K Deol, Marie-Annick Letzelter, Eric Robert Strieter, Sonja Lorenz

J Biol Chem. 2019 Apr 12;294(15):6113-6129.

PMID: 30737286

1

Crystal Structure of the Catalytic C-lobe of the HECT-type Ubiquitin Ligase E6AP

Lena K Ries, Anna K L Liess, Christian G Feiler, Donald E Spratt, Edward D Lowe, Sonja Lorenz

Protein Sci. 2020 Jun;29(6):1550-1554.

PMID: 31994269

1

Role of Ubiquitin and the HPV E6 Oncoprotein in E6AP-mediated Ubiquitination

Franziska Mortensen, Daniel Schneider, Tanja Barbic, Anna Sladewska-Marquardt, Simone Kühnle, Andreas Marx, Martin Scheffner

Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9872-7.

PMID: 26216987

1

The Active Form of E6-associated Protein (E6AP)/UBE3A Ubiquitin Ligase Is an Oligomer

Virginia P Ronchi, Jennifer M Klein, Daniel J Edwards, Arthur L Haas

J Biol Chem. 2014 Jan 10;289(2):1033-48.

PMID: 24273172

1

UBE3A-mediated Regulation of Imprinted Genes and Epigenome-Wide Marks in Human Neurons

S Jesse Lopez, Keith Dunaway, M Saharul Islam, Charles Mordaunt, Annie Vogel Ciernia, Makiko Meguro-Horike, Shin-Ichi Horike, David J Segal, Janine M LaSalle

Epigenetics. 2017;12(11):982-990.

PMID: 28925810

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