Ubiquitin E1 Inhibitor, PYR-41 - Analytical Products / Alfa Chemistry

CAT	IAR42410924
Molecular Weight	371.30

Description	The Ubiquitin E1 Inhibitor, PYR-41 controls the biological activity of Ubiquitin E1. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
Solubility	DMSO: 10 mg/mL
Assay	≥90% (sum of two isomers, HPLC)
Color	dark purple
Form	solid; protect from light
Size	25MG
Storage Conditions	-20C

1

Administration of Ubiquitin-Activating Enzyme UBA1 Inhibitor PYR-41 Attenuates Angiotensin II-induced Cardiac Remodeling in Mice

Qing Shu, Song Lai, Xiao-Mei Wang, Yun-Long Zhang, Xiao-Lei Yang, Hai-Lian Bi, Hui-Hua Li

Biochem Biophys Res Commun. 2018 Oct 20;505(1):317-324.

PMID: 30249396

1

Differential Contributions of Ubiquitin-Modified APOBEC3G Lysine Residues to HIV-1 Vif-Induced Degradation

Tiffany Turner, Qiujia Shao, Weiran Wang, Yudi Wang, Chenliang Wang, Ballington Kinlock, Bindong Liu

J Mol Biol. 2016 Aug 28;428(17):3529-39.

PMID: 27297094

1

Regulation of Sperm Capacitation by the 26S Proteasome: An Emerging New Paradigm in Spermatology

Karl Kerns, Patricio Morales, Peter Sutovsky

Biol Reprod. 2016 May;94(5):117.

PMID: 27053366

1

Ubiquitin-activating Enzyme (UBA1) Is Required for Sperm Capacitation, Acrosomal Exocytosis and Sperm-Egg Coat Penetration During Porcine Fertilization

Y-J Yi, S W Zimmerman, G Manandhar, J F Odhiambo, C Kennedy, V Jonáková, P Maňásková-Postlerová, M Sutovsky, C-S Park, P Sutovsky

Int J Androl. 2012 Apr;35(2):196-210.

PMID: 21950462

1

Ubiquitin-activating Enzyme E1 Inhibitor PYR-41 Retards Sperm Enlargement After Fusion to the Egg

Keiichi Yoshida, Woojin Kang, Akihiro Nakamura, Natsuko Kawano, Maito Hanai, Mami Miyado, Yoshitaka Miyamoto, Maki Iwai, Toshio Hamatani, Hidekazu Saito, Kenji Miyado, Akihiro Umezawa

Reprod Toxicol. 2018 Mar;76:71-77.

PMID: 29355596

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