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UMI-77

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For Research Use Only | Not For Clinical Use
CATAP518303203
CAS518303-20-3
MDL NumberMFCD03471890
Molecular Weight468.34
InChI KeyWUGANDSUVKXMEC-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Broad Targeting of Resistance to Apoptosis in Cancer

Ramzi M Mohammad, Irfana Muqbil, Leroy Lowe, Clement Yedjou, Hsue-Yin Hsu, Liang-Tzung Lin, Markus David Siegelin, Carmela Fimognari, Nagi B Kumar, Q Ping Dou, Huanjie Yang, Abbas K Samadi, Gian Luigi Russo, etc.

Semin Cancer Biol. 2015 Dec;35 Suppl(0):S78-S103.

PMID: 25936818

1

Confounding Off-Target Effects of BH3 Mimetics at Commonly Used Concentrations: MIM1, UMI-77, and A-1210477

David J Mallick, Ryan S Soderquist, Darcy Bates, Alan Eastman

Cell Death Dis. 2019 Feb 22;10(3):185.

PMID: 30796196

1

Dual Functions for OVAAL in Initiation of RAF/MEK/ERK Prosurvival Signals and Evasion of p27-mediated Cellular Senescence

Ben Sang, Yuan Yuan Zhang, Su Tang Guo, Ling Fei Kong, Qiong Cheng, Guang Zhi Liu, Rick F Thorne, Xu Dong Zhang, Lei Jin, Mian Wu

Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11661-E11670.

PMID: 30478051

1

Survival of Midbrain Dopamine Neurons Depends on the Bcl2 Factor Mcl1

Edward J Robinson, Sebastian P Aguiar, Willemieke M Kouwenhoven, Dorinde S Starmans, Lars von Oerthel, Marten P Smidt, Lars P van der Heide

Cell Death Discov. 2018 Nov 21;4:107.

PMID: 30479840

1

UMI-77 Primes Glioma Cells for TRAIL-induced Apoptosis by Unsequestering Bim and Bak From Mcl-1

Ji-Wei Liu, Zhi-Chuan Zhu, Kui Li, Hong-Tao Wang, Zhi-Qi Xiong, Jing Zheng

Mol Cell Biochem. 2017 Aug;432(1-2):55-65.

PMID: 28337703

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