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UNC0642

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For Research Use Only | Not For Clinical Use
CATIAR4245466
MDL NumberMFCD28044322
Molecular Weight546.70
InChI KeyRNAMYOYQYRYFQY-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Amelioration of Autism-Like Social Deficits by Targeting Histone Methyltransferases EHMT1/2 in Shank3-deficient Mice

Zi-Jun Wang, Ping Zhong, Kaijie Ma, Ji-Seon Seo, Fengwei Yang, Zihua Hu, Freddy Zhang, Lin Lin, Jie Wang, Tao Liu, Emmanuel Matas, Paul Greengard, Zhen Yan

Mol Psychiatry. 2019 Jan 18;10.1038/s41380-019-0351-2.

PMID: 30659288

1

DZNep and UNC0642 Enhance in Vitro Developmental Competence of Cloned Pig Embryos

Chengfa Zhao, Junsong Shi, Rong Zhou, Xiaoyan He, Huaqiang Yang, Zhenfang Wu

Reproduction. 2018 Apr 1;157(4):359-369.

PMID: 30730848

1

Inhibition of the G9a/GLP Histone Methyltransferase Complex Modulates Anxiety-Related Behavior in Mice

Dong-Yao Wang, Joel Kosowan, James Samsom, Laura Leung, Kai-Lai Zhang, Ying-Xiang Li, Yan Xiong, Jian Jin, Arturas Petronis, Gabriel Oh, Albert H C Wong

Acta Pharmacol Sin. 2018 May;39(5):866-874.

PMID: 29417943

1

Pharmacological Inhibition of G9a/GLP Restores Cognition and Reduces Oxidative Stress, Neuroinflammation and β-Amyloid Plaques in an Early-Onset Alzheimer's Disease Mouse Model

Christian Griñán-Ferré, Laura Marsal-García, Aina Bellver-Sanchis, Shukkoor Muhammed Kondengaden, Ravi Chakra Turga, Santiago Vázquez, Mercè Pallàs

Aging (Albany NY). 2019 Dec 4;11(23):11591-11608.

PMID: 31804189

1

Targeting the Histone Methyltransferase G9a Activates Imprinted Genes and Improves Survival of a Mouse Model of Prader-Willi Syndrome

Yuna Kim, Hyeong-Min Lee, Yan Xiong, Noah Sciaky, Samuel W Hulbert, Xinyu Cao, Jeffrey I Everitt, Jian Jin, Bryan L Roth, Yong-Hui Jiang

Nat Med. 2017 Feb;23(2):213-222.

PMID: 28024084

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