CAS 1431612-23-5 UNC1999 - Analytical Products / Alfa Chemistry

CAT	AP1431612235
CAS	1431612-23-5
MDL Number	MFCD26960958
Molecular Weight	569.74
InChI Key	DPJNKUOXBZSZAI-UHFFFAOYSA-N

Description	≥98% (HPLC)
Solubility	DMSO: 15 mg/mL, clear
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	5MG, 25MG
Storage Conditions	2-8°C

1

Dual Inhibition of EZH2 and EZH1 Sensitizes PRC2-Dependent Tumors to Proteasome Inhibition

Ola Rizq, Naoya Mimura, Motohiko Oshima, Atsunori Saraya, Shuhei Koide, Yuko Kato, Kazumasa Aoyama, Yaeko Nakajima-Takagi, Changshan Wang, Tetsuhiro Chiba, Anqi Ma, Jian Jin, Tohru Iseki, Chiaki Nakaseko, etc.

Clin Cancer Res. 2017 Aug 15;23(16):4817-4830.

PMID: 28490465

1

EZH2 Inhibition Suppresses Bladder Cancer Cell Growth and Metastasis via the JAK2/STAT3 Signaling Pathway

Zhiyuan Chen, Yang Du, Xiuheng Liu, Hui Chen, Xiaodong Weng, Jia Guo, Min Wang, Xiao Wang, Lei Wang

Oncol Lett. 2019 Jul;18(1):907-915.

PMID: 31289569

1

Increased EZH2 Expression in Prostate Cancer Is Associated With Metastatic Recurrence Following External Beam Radiotherapy

Xiaoning Wu, Helen Scott, Sigrid V Carlsson, Daniel D Sjoberg, Lucia Cerundolo, Hans Lilja, Remko Prevo, Guillaume Rieunier, Valentine Macaulay, Geoffrey S Higgins, Clare L Verrill, Alastair D Lamb, Vincent T Cunliffe, etc.

Prostate. 2019 Jul;79(10):1079-1089.

PMID: 31104332

1

Mechanisms of Resistance to EZH2 Inhibitors in Diffuse Large B-cell Lymphomas

Malik Bisserier, Narendra Wajapeyee

Blood. 2018 May 10;131(19):2125-2137.

PMID: 29572378

1

Selective Inhibition of EZH2 and EZH1 Enzymatic Activity by a Small Molecule Suppresses MLL-rearranged Leukemia

Bowen Xu, Doan M On, Anqi Ma, Trevor Parton, Kyle D Konze, Samantha G Pattenden, David F Allison, Ling Cai, Shira Rockowitz, Shichong Liu, Ying Liu, Fengling Li, Masoud Vedadi, Stephen V Frye, Benjamin A Garcia, etc.

Blood. 2015 Jan 8;125(2):346-57.

PMID: 25395428

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