UTX human - Analytical Products / Alfa Chemistry

CAT

IAR42416067

Description	recombinant, expressed in baculovirus infected Sf9 cells, ≥40% (SDS-PAGE)
Assay	≥40% (SDS-PAGE)
Form	aqueous solution
Size	20μG
Storage Conditions	−70°C

1

Differentiation of Human Pluripotent Stem Cells Into Neurons or Cortical Organoids Requires Transcriptional Co-Regulation by UTX and 53BP1

Xiaoyang Yang, Beisi Xu, Brett Mulvey, Myron Evans, Samuel Jordan, Yong-Dong Wang, Vishwajeeth Pagala, Junmin Peng, Yiping Fan, Arishna Patel, Jamy C Peng

Nat Neurosci. 2019 Mar;22(3):362-373.

PMID: 30718900

1

Histone Demethylase KDM6A Directly Senses Oxygen to Control Chromatin and Cell Fate

Abhishek A Chakraborty, Tuomas Laukka, Matti Myllykoski, Alison E Ringel, Matthew A Booker, Michael Y Tolstorukov, Yuzhong Jeff Meng, Samuel R Meier, Rebecca B Jennings, Amanda L Creech, Zachary T Herbert, etc.

Science. 2019 Mar 15;363(6432):1217-1222.

PMID: 30872525

1

In Vivo CRISPR Screening Unveils Histone Demethylase UTX as an Important Epigenetic Regulator in Lung Tumorigenesis

Qibiao Wu, Yahui Tian, Jian Zhang, Xinyuan Tong, Hsinyi Huang, Shuai Li, Hong Zhao, Ying Tang, Chongze Yuan, Kun Wang, Zhaoyuan Fang, Lei Gao, Xin Hu, Fuming Li, Zhen Qin, Shun Yao, Ting Chen, Haiquan Chen, etc.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E3978-E3986.

PMID: 29632194

1

UTX Mutations in Human Cancer

Lu Wang, Ali Shilatifard

Cancer Cell. 2019 Feb 11;35(2):168-176.

PMID: 30753822

1

UTX-mediated Enhancer and Chromatin Remodeling Suppresses Myeloid Leukemogenesis Through Noncatalytic Inverse Regulation of ETS and GATA Programs

Malgorzata Gozdecka, Eshwar Meduri, Milena Mazan, Konstantinos Tzelepis, Monika Dudek, Andrew J Knights, Mercedes Pardo, Lu Yu, Jyoti S Choudhary, Emmanouil Metzakopian, Vivek Iyer, Haiyang Yun, Naomi Park, etc.

Nat Genet. 2018 Jun;50(6):883-894.

PMID: 29736013

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