VEGF Inhibitor, Flt₂₋₁₁ - Analytical Products / Alfa Chemistry

CAT	IAR42415724
Molecular Weight	1273.56

Description	The VEGF Inhibitor, Flt2-11 controls the biological activity of VEGF. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Solubility	acetonitrile: 20%; DMSO: 5 mg/mL
Assay	≥95% (HPLC)
Color	white
Form	lyophilized solid; desiccated
Size	1MG
Storage Conditions	+2C to +8C

1

EphrinB2/EphB4 Signaling Regulates Non-Sprouting Angiogenesis by VEGF

Elena Groppa, Sime Brkic, Andrea Uccelli, Galina Wirth, Petra Korpisalo-Pirinen, Maria Filippova, Boris Dasen, Veronica Sacchi, Manuele Giuseppe Muraro, Marianna Trani, Silvia Reginato, Roberto Gianni-Barrera, etc.

EMBO Rep. 2018 May;19(5):e45054.

PMID: 29643120

1

Protease-activated Receptor 2 Protects Against VEGF Inhibitor-Induced Glomerular Endothelial and Podocyte Injury

Yuji Oe, Tomofumi Fushima, Emiko Sato, Akiyo Sekimoto, Kiyomi Kisu, Hiroshi Sato, Junichi Sugawara, Sadayoshi Ito, Nobuyuki Takahashi

Sci Rep. 2019 Feb 27;9(1):2986.

PMID: 30814628

1

Rationally Combining anti-VEGF Therapy With Checkpoint Inhibitors in Hepatocellular Carcinoma

Tai Hato, Andrew X Zhu, Dan G Duda

Immunotherapy. 2016;8(3):299-313.

PMID: 26865127

1

SRPKIN-1: A Covalent SRPK1/2 Inhibitor That Potently Converts VEGF From Pro-angiogenic to Anti-angiogenic Isoform

John M Hatcher, Guowei Wu, Chuyue Zeng, Jie Zhu, Fan Meng, Sherrina Patel, Wenqiu Wang, Scott B Ficarro, Alan L Leggett, Chelsea E Powell, Jarrod A Marto, Kang Zhang, Jacky Chi Ki Ngo, Xiang-Dong Fu, Tinghu Zhang, etc.

Cell Chem Biol. 2018 Apr 19;25(4):460-470.e6.

PMID: 29478907

1

Vascular Toxicities With VEGF Inhibitor Therapies-Focus on Hypertension and Arterial Thrombotic Events

Rhian M Touyz, Sandra M S Herrmann, Joerg Herrmann

J Am Soc Hypertens. 2018 Jun;12(6):409-425.

PMID: 29703600

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