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VHL human

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For Research Use Only | Not For Clinical Use
CATIAR42414964
Descriptionrecombinant, expressed in insect cells, ≥70% (SDS-PAGE)
Assay≥70% (SDS-PAGE)
Colorclear colorless
Formfrozen liquid
Size5μG
Storage Conditions−70°C
1

Combined Mutation in Vhl, Trp53 and Rb1 Causes Clear Cell Renal Cell Carcinoma in Mice

Sabine Harlander, Désirée Schönenberger, Nora C Toussaint, Michael Prummer, Antonella Catalano, Laura Brandt, Holger Moch, Peter J Wild, Ian J Frew

Nat Med. 2017 Jul;23(7):869-877.

PMID: 28553932

1

Fructose-1,6-bisphosphatase Opposes Renal Carcinoma Progression

Bo Li, Bo Qiu, David S M Lee, Zandra E Walton, Joshua D Ochocki, Lijoy K Mathew, Anthony Mancuso, Terence P F Gade, Brian Keith, Itzhak Nissim, M Celeste Simon

Nature. 2014 Sep 11;513(7517):251-5.

PMID: 25043030

1

HIF-independent Synthetic Lethality Between CDK4/6 Inhibition and VHL Loss Across Species

Hilary E Nicholson, Zeshan Tariq, Benjamin E Housden, Rebecca B Jennings, Laura A Stransky, Norbert Perrimon, Sabina Signoretti, William G Kaelin Jr

Sci Signal. 2019 Oct 1;12(601):eaay0482.

PMID: 31575731

1

Targeting Renal Cell Carcinoma With a HIF-2 Antagonist

Wenfang Chen, Haley Hill, Alana Christie, Min Soo Kim, Eboni Holloman, Andrea Pavia-Jimenez, Farrah Homayoun, Yuanqing Ma, Nirav Patel, Paul Yell, Guiyang Hao, Qurratulain Yousuf, Allison Joyce, Ivan Pedrosa, etc.

Nature. 2016 Nov 3;539(7627):112-117.

PMID: 27595394

1

The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma

Amrita M Nargund, Can G Pham, Yiyu Dong, Patricia I Wang, Hatice U Osmangeyoglu, Yuchen Xie, Omer Aras, Song Han, Toshinao Oyama, Shugaku Takeda, Chelsea E Ray, Zhenghong Dong, Mathieu Berge, A Ari Hakimi, etc.

Cell Rep. 2017 Mar 21;18(12):2893-2906.

PMID: 28329682

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