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VX-680

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For Research Use Only | Not For Clinical Use
CATAP639089546
CAS639089-54-6
Structure
MDL NumberMFCD13185152
Molecular Weight464.59
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size10MG
Storage Conditions2-8°C
1

[Effect of Aurora Inhibitor VX-680 on Proliferation and Apoptosis of CML Cells]

Yue Yin, Hui-Yan Sun, Xiao-Lin Li, Feng-Jun Xiao, Li-Sheng Wang

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2014 Dec;22(6):1540-4.

PMID: 25543471

1

Combined Treatment With ABT-737 and VX-680 Induces Apoptosis in Bcl-2- And c-FLIP-overexpressing Breast Carcinoma Cells

Jung Eun Choi, Seon Min Woo, Kyoung-Jin Min, Su Hwan Kang, Soo Jung Lee, Taeg Kyu Kwon

Oncol Rep. 2015 Mar;33(3):1395-401.

PMID: 25592064

1

Effects of the Aurora Kinase Inhibitor VX-680 on Anaplastic Thyroid Cancer-Derived Cell Lines

Yannick Arlot-Bonnemains, Enke Baldini, Benedicte Martin, Jean-Guy Delcros, Matteo Toller, Francesco Curcio, Francesco S Ambesi-Impiombato, Massimino D'Armiento, Salvatore Ulisse

Endocr Relat Cancer. 2008 Jun;15(2):559-68.

PMID: 18430894

1

VX-680 Induces p53-mediated Apoptosis in Human Cholangiocarcinoma Cells

Juan Liu, Cheng-Yong Qin

Anticancer Drugs. 2018 Nov;29(10):1004-1010.

PMID: 30080692

1

VX-680 Inhibits Aurora A and Aurora B Kinase Activity in Human Cells

Rebecca K Tyler, Natalia Shpiro, Rodolfo Marquez, Patrick A Eyers

Cell Cycle. 2007 Nov 15;6(22):2846-54.

PMID: 18032922

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