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WAY-252623

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For Research Use Only | Not For Clinical Use
CATAP875787078
CAS875787-07-8
Structure
Molecular Weight422.78
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

Discovery and Implementation of Transcriptional Biomarkers of Synthetic LXR Agonists in Peripheral Blood Cells

Elizabeth A DiBlasio-Smith, Maya Arai, Elaine M Quinet, Mark J Evans, Tad Kornaga, Michael D Basso, Liang Chen, Irene Feingold, Anita R Halpern, Qiang-Yuan Liu, Ponnal Nambi, Dawn Savio, Shuguang Wang, etc.

J Transl Med. 2008 Oct 16;6:59.

PMID: 18925943

1

LXR Ligand Lowers LDL Cholesterol in Primates, Is Lipid Neutral in Hamster, and Reduces Atherosclerosis in Mouse

Elaine M Quinet, Michael D Basso, Anita R Halpern, David W Yates, Robert J Steffan, Valerie Clerin, Christine Resmini, James C Keith, Thomas J Berrodin, Irene Feingold, Wenyan Zhong, Helen B Hartman, Mark J Evans, etc.

J Lipid Res. 2009 Dec;50(12):2358-70.

PMID: 19318684

1

Promoting Intestinal Lymphatic Transport Targets a liver-X Receptor (LXR) Agonist (WAY-252,623) to Lymphocytes and Enhances Immunomodulation

Enyuan Cao, Anna Lindgren, Sofia Martinsson, Luojuan Hu, Lennart Lindfors, Kalle Sigfridsson, Urban Skantze, Erik Michaëlsson, Natalie L Trevaskis, Christopher J H Porter

J Control Release. 2019 Feb 28;296:29-39.

PMID: 30611901

1

Synergistic Effect of Liver X Receptor Activation and Simvastatin on Plaque Regression and Stabilization: An Magnetic Resonance Imaging Study in a Model of Advanced Atherosclerosis

Chiara Giannarelli, Giovanni Cimmino, Thomas M Connolly, Borja Ibanez, Josè M Garcia Ruiz, Matilde Alique, M Urooj Zafar, Valentin Fuster, Giora Feuerstein, Juan J Badimon

Eur Heart J. 2012 Jan;33(2):264-73.

PMID: 21606082

1

The LXR-623-induced Long Non-Coding RNA LINC01125 Suppresses the Proliferation of Breast Cancer Cells via PTEN/AKT/p53 Signaling Pathway

Weijun Wan, Yongying Hou, Ke Wang, Yue Cheng, Xia Pu, Xiufeng Ye

Cell Death Dis. 2019 Mar 13;10(3):248.

PMID: 30867411

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