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WDR5-0103

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For Research Use Only | Not For Clinical Use
CATAP890190224
CAS890190-22-4
Molecular Weight383.44
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Storage Conditions2-8°C
1

HBx Protein Contributes to Liver Carcinogenesis by H3K4me3 Modification Through Stabilizing WD Repeat Domain 5 Protein

Weiwu Gao, Zhengcai Jia, Yi Tian, Penghui Yang, Hui Sun, Chenhui Wang, Yi Ding, Mengjie Zhang, Yi Zhang, Di Yang, Zhiqiang Tian, Jian Zhou, Zhihua Ruan, Yuzhang Wu, Bing Ni

Hepatology. 2020 May;71(5):1678-1695.

PMID: 31544250

1

Inhibiting MLL1-WDR5 Interaction Ameliorates Neuropathic Allodynia by Attenuating Histone H3 Lysine 4 Trimethylation-Dependent Spinal mGluR5 Transcription

Tzer-Bin Lin, Cheng-Yuan Lai, Ming-Chun Hsieh, Yu-Cheng Ho, Hsueh-Hsiao Wang, Po-Sheng Yang, Jen-Kun Cheng, Gin-Den Chen, Soo-Cheen Ng, Hsien-Yu Peng

Pain. 2020 Apr 23.

PMID: 32345914

1

Structure-based Design of Ester Compounds to Inhibit MLL Complex Catalytic Activity by Targeting Mixed Lineage Leukemia 1 (MLL1)-WDR5 Interaction

Dong-Dong Li, Zhi-Hui Wang, Wei-Lin Chen, Yi-Yue Xie, Qi-Dong You, Xiao-Ke Guo

Bioorg Med Chem. 2016 Nov 15;24(22):6109-6118.

PMID: 27720555

1

The Histone H3 Lysine 4 Presenter WDR5 as an Oncogenic Protein and Novel Epigenetic Target in Cancer

Kebin Lu, He Tao, Xiaomin Si, Qingjuan Chen

Front Oncol. 2018 Nov 14;8:502.

PMID: 30488017

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