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WHI-P154

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For Research Use Only | Not For Clinical Use
CATAP211555043-B
CAS211555-04-3
Structure
Molecular Weight376.20
Description≥98% (HPLC)
SolubilityDMSO: 1 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to brown
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Inhibition of Human Glioblastoma Cell Adhesion and Invasion by 4-(4'-hydroxylphenyl)-amino-6,7-dimethoxyquinazoline (WHI-P131) and 4-(3'-bromo-4'-hydroxylphenyl)-amino-6,7-dimethoxyquinazoline (WHI-P154)

R K Narla, X P Liu, D Klis, F M Uckun

Clin Cancer Res. 1998 Oct;4(10):2463-71.

PMID: 9796979

1

Inhibition of the Antigen-Induced Activation of Rodent Mast Cells by Putative Janus Kinase 3 Inhibitors WHI-P131 and WHI-P154 in a Janus Kinase 3-independent Manner

Watchara Linwong, Noriyasu Hirasawa, Suzue Aoyama, Hirofumi Hamada, Takashi Saito, Kazuo Ohuchi

Br J Pharmacol. 2005 Jul;145(6):818-28.

PMID: 15852029

1

JAK Inhibitors AG-490 and WHI-P154 Decrease IFN-gamma-induced iNOS Expression and NO Production in Macrophages

Outi Sareila, Riku Korhonen, Outi Kärpänniemi, Riina Nieminen, Hannu Kankaanranta, Eeva Moilanen

Mediators Inflamm. 2006;2006(2):16161.

PMID: 16883061

1

The JAK3 Inhibitor WHI-P154 Prevents PDGF-evoked Process Outgrowth in Human Neural Precursor Cells

G R Richards, A J Smith, P Cuddon, Q P Ma, M Leveridge, J Kerby, H L Roderick, M D Bootman, P B Simpson

J Neurochem. 2006 Apr;97(1):201-10.

PMID: 16515549

1

WHI-P154 Enhances the Chemotherapeutic Effect of Anticancer Agents in ABCG2-overexpressing Cells

Hui Zhang, Yun-Kai Zhang, Yi-Jun Wang, Rishil J Kathawala, Atish Patel, Hua Zhu, Kamlesh Sodani, Tanaji T Talele, Suresh V Ambudkar, Zhe-Sheng Chen, Li-Wu Fu

Cancer Sci. 2014 Aug;105(8):1071-8.

PMID: 24903205

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