CAS 19545-26-7 Wortmannin - CAS 19545-26-7 - Analytical Products / Alfa Chemistry

CAT	AP19545267-B
CAS	19545-26-7
Structure
Molecular Weight	428.43

Description	Wortmannin, CAS 19545-26-7, is a cell-permeable, potent, selective, and irreversible inhibitor of PI3-Kinase (IC₅₀ = 5 nM). Does not affect any upstream signaling events.
Solubility	DMSO: 25 mg/mL
Assay	≥98% (HPLC)
Color	white to off-white
Form	solid; protect from light
Size	1MG
Storage Conditions	-20C

1

A Role for Phosphoinositides in Tyrosine Phosphorylation of p125 Focal Adhesion Kinase in Rat Pancreatic Acini

J A Rosado, G M Salido, L J García

Cell Signal. 2000 Mar;12(3):173-82.

PMID: 10704824

1

Activation of Wiskott-Aldrich Syndrome Protein and Its Association With Other Proteins by Stromal Cell-Derived factor-1alpha Is Associated With Cell Migration in a T-lymphocyte Line

Seiichi Okabe, Seiji Fukuda, Hal E Broxmeyer

Exp Hematol. 2002 Jul;30(7):761-6.

PMID: 12135674

1

Autophagy Regulates Exosomal Release of Prions in Neuronal Cells

Basant A Abdulrahman, Dalia H Abdelaziz, Hermann M Schatzl

J Biol Chem. 2018 Jun 8;293(23):8956-8968.

PMID: 29700113

1

Insulin-like Growth Factor I Stimulates Tyrosine Phosphorylation of p130(Cas), Focal Adhesion Kinase, and Paxillin. Role of Phosphatidylinositol 3'-kinase and Formation of a p130(Cas).Crk Complex

A Casamassima, E Rozengurt

J Biol Chem. 1998 Oct 2;273(40):26149-56.

PMID: 9748296

1

Tyrosine Phosphorylation of p130(cas) by Bombesin, Lysophosphatidic Acid, Phorbol Esters, and Platelet-Derived Growth Factor. Signaling Pathways and Formation of a p130(cas)-Crk Complex

A Casamassima, E Rozengurt

J Biol Chem. 1997 Apr 4;272(14):9363-70.

PMID: 9083073

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