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WY-14643

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For Research Use Only | Not For Clinical Use
CATAP50892234
CAS50892-23-4
MDL NumberMFCD00191335
Molecular Weight323.80
InChI KeySZRPDCCEHVWOJX-UHFFFAOYSA-N
Size10MG, 50MG
1

Multifaceted Mechanisms of WY-14643 to Stabilize the Blood-Brain Barrier in a Model of Traumatic Brain Injury

Winfried Neuhaus, Tobias Krämer, Anja Neuhoff, Christina Gölz, Serge C Thal, Carola Y Förster

Front Mol Neurosci. 2017 May 26;10:149.

PMID: 28603485

1

PPARα Agonist WY-14643 Induces SIRT1 Activity in Rat Fatty Liver Ischemia-Reperfusion Injury

Eirini Pantazi, Emma Folch-Puy, Mohamed Bejaoui, Arnau Panisello, Ana Teresa Varela, Anabela Pinto Rolo, Carlos Marques Palmeira, Joan Roselló-Catafau

Biomed Res Int. 2015;2015:894679.

PMID: 26539534

1

PPAR-α Agonist WY-14643 Inhibits LPS-Induced Inflammation in Synovial Fibroblasts via NF-kB Pathway

Degang Huang, Quanlai Zhao, Hongfei Liu, Yongjie Guo, Hongguang Xu

J Mol Neurosci. 2016 Aug;59(4):544-53.

PMID: 27339772

1

WY-14643 Regulates CYP1B1 Expression Through Peroxisome Proliferator-Activated Receptor α-Mediated Signaling in Human Breast Cancer Cells

Yong Pil Hwang, Seong Su Won, Sun Woo Jin, Gi Ho Lee, Thi Hoa Pham, Jae Ho Choi, Keon Wook Kang, Hye Gwang Jeong

Int J Mol Sci. 2019 Nov 25;20(23):5928.

PMID: 31775380

1

WY-14643, a Selective Agonist of Peroxisome Proliferator-Activated receptor-α, Ameliorates Lipopolysaccharide-Induced Depressive-Like Behaviors by Preventing Neuroinflammation and Oxido-Nitrosative Stress in Mice

Rongrong Yang, Peng Wang, Zhuo Chen, Wenfeng Hu, Yu Gong, Wei Zhang, Chao Huang

Pharmacol Biochem Behav. 2017 Feb;153:97-104.

PMID: 28017641

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