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XBD173

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For Research Use Only | Not For Clinical Use
CATAP226954047
CAS226954-04-7
Structure
MDL NumberMFCD07772312
Molecular Weight401.46
InChI KeyNBMBIEOUVBHEBM-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Antidepressant-like Effects of Translocator Protein (18 kDa) Ligand ZBD-2 in Mouse Models of Postpartum Depression

Xu-Bo Li, An Liu, Le Yang, Kun Zhang, Yu-Mei Wu, Ming-Gao Zhao, Shui-Bing Liu

Mol Brain. 2018 Mar 5;11(1):12.

PMID: 29506545

1

Targeting Translocator Protein (18 kDa) (TSPO) Dampens Pro-Inflammatory Microglia Reactivity in the Retina and Protects From Degeneration

Rebecca Scholz, Albert Caramoy, Mohajeet B Bhuckory, Khalid Rashid, Mei Chen, Heping Xu, Christian Grimm, Thomas Langmann

J Neuroinflammation. 2015 Nov 2;12:201.

PMID: 26527153

1

The Agonistic TSPO Ligand XBD173 Attenuates the Glial Response Thereby Protecting Inner Retinal Neurons in a Murine Model of Retinal Ischemia

Kristin Mages, Felix Grassmann, Herbert Jägle, Rainer Rupprecht, Bernhard H F Weber, Stefanie M Hauck, Antje Grosche

J Neuroinflammation. 2019 Feb 18;16(1):43.

PMID: 30777091

1

Translocator Protein (18 kDa) (TSPO) Is Expressed in Reactive Retinal Microglia and Modulates Microglial Inflammation and Phagocytosis

Marcus Karlstetter, Caroline Nothdurfter, Alexander Aslanidis, Katharina Moeller, Felicitas Horn, Rebecca Scholz, Harald Neumann, Bernhard H F Weber, Rainer Rupprecht, Thomas Langmann

J Neuroinflammation. 2014 Jan 8;11:3.

PMID: 24397957

1

TSPO Ligands Boost Mitochondrial Function and Pregnenolone Synthesis

Imane Lejri, Amandine Grimm, François Hallé, Mustapha Abarghaz, Christian Klein, Michel Maitre, Martine Schmitt, Jean-Jacques Bourguignon, Ayikoe Guy Mensah-Nyagan, Frederic Bihel, Anne Eckert

J Alzheimers Dis. 2019;72(4):1045-1058.

PMID: 31256132

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