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Xestospongin C

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For Research Use Only | Not For Clinical Use
CATAP88903699
CAS88903-69-9
Structure
MDL NumberMFCD01862629
Molecular Weight446.71
InChI KeyPQYOPBRFUUEHRC-HCKQMYSWSA-N
Descriptionfilm
SolubilityDMSO: soluble
Colorcolorless
Formfilm
Linear FormulaC28 H50 N2 O2
Size10μG, 50μG
Storage Conditions−20°C
1

Inhibitory Mechanism of xestospongin-C on Contraction and Ion Channels in the Intestinal Smooth Muscle

Hiroshi Ozaki, Masatoshi Hori, Yoon-Sun Kim, Seong-Chun Kwon, Duck-Sun Ahn, Hiroshi Nakazawa, Motomasa Kobayashi, Hideaki Karaki

Br J Pharmacol. 2002 Dec;137(8):1207-12.

PMID: 12466229

1

Xestospongin C Induces Monocytic Differentiation of HL60 Cells Through Activation of the ERK Pathway

Dong-Oh Moon, Yukihiro Asami, Mun-Ock Kim, Jae-Hyuk Jang, Bo Yeon Kim, Jong Seog Ahn, Gi-Young Kim, Sung Gyu Yun

Food Chem Toxicol. 2013 May;55:505-12.

PMID: 23395717

1

Xestospongin C, a Novel Blocker of IP3 Receptor, Attenuates the Increase in Cytosolic Calcium Level and Degranulation That Is Induced by Antigen in RBL-2H3 Mast Cells

Tatsuya Oka, Koichi Sato, Masatoshi Hori, Hiroshi Ozaki, Hideaki Karaki

Br J Pharmacol. 2002 Apr;135(8):1959-66.

PMID: 11959799

1

Xestospongin C, a Reversible IP3 Receptor Antagonist, Alleviates the Cognitive and Pathological Impairments in APP/PS1 Mice of Alzheimer's Disease

Zhao-Jun Wang, Fang Zhao, Chen-Fang Wang, Xiu-Min Zhang, Yi Xiao, Fang Zhou, Mei-Na Wu, Jun Zhang, Jin-Shun Qi, Wei Yang

J Alzheimers Dis. 2019;72(4):1217-1231.

PMID: 31683484

1

Xestospongin C, a Selective and Membrane-Permeable Inhibitor of IP(3) Receptor, Attenuates the Positive Inotropic Effect of Alpha-Adrenergic Stimulation in Guinea-Pig Papillary Muscle

S Miyamoto, M Izumi, M Hori, M Kobayashi, H Ozaki, H Karaki

Br J Pharmacol. 2000 Jun;130(3):650-4.

PMID: 10821794

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