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YH439

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For Research Use Only | Not For Clinical Use
CATAP130112424
CAS130112-42-4
MDL NumberMFCD02752797
Molecular Weight330.45
InChI KeyWOUUWUGULFOVHG-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥5 mg/mL
Assay≥98% (HPLC)
Formsolid
Size5MG, 25MG
Storage Conditions2-8°C
1

Effect of Food on the Pharmacokinetics of YH439 and Its Metabolites in Rats

M K Kim, B N Ahn, J K Yoo, J W Lee

Arch Pharm Res. 1997 Dec;20(6):629-32.

PMID: 18982270

1

Species Differences in Pharmacokinetics of a Hepatoprotective Agent, YH439, and Its Metabolites, M4, M5, and M7, After Intravenous and Oral Administration to Rats, Rabbits, and Dogs

W H Yoon, J K Yoo, J W Lee, C K Shim, M G Lee

Drug Metab Dispos. 1998 Feb;26(2):152-63.

PMID: 9456302

1

Suppression of Rat Hepatic Cytochrome P450 2E1 Expression by Isopropyl 2-(1,3-dithioetane-2-ylidene)-2-[N-(4-methyl-thiazol-2-yl)carbamoyl] Acetate (YH439), an Experimental Hepatoprotectant: Protective Role Against Hepatic Injury

E Y Choi, S G Kim, J W Lee, J K Yoo, J K Shin, N D Kim

Biochem Pharmacol. 1996 Oct 25;52(8):1219-25.

PMID: 8937429

1

The Transport of a Hepatoprotective Agent, Isopropryl 2-(1-3-dithiethane-2-ylidene)-2[N-(4-methyl-thiazole-2-yl) Carbamoyl] Acetate (YH439), Across Caco-2 Cell Monolayers

H W Park, S J Chung, H J Kuh, S J Chung, M G Lee, C K Shim

Arch Pharm Res. 2001 Dec;24(6):584-9.

PMID: 11794540

1

Thermal Reversible Microemulsion System for Poorly Water-Soluble YH439 for Oral Delivery

Dong-Han Han, Zhe-Hu Jin, Yan-Zhe Jin, Xue-Zhe Yin, Yuan-Yuan Shen, Zhong-Gao Gao

Chem Pharm Bull (Tokyo). 2010 Jan;58(1):11-5.

PMID: 20045958

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