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Yoda1

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For Research Use Only | Not For Clinical Use
CATAP448947817
CAS448947-81-7
Molecular Weight355.27
Description≥98% (HPLC)
SolubilityDMSO: 15 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Activation of Piezo1 Sensitizes Cells to TRAIL-mediated Apoptosis Through Mitochondrial Outer Membrane Permeability

Jacob M Hope, Maria Lopez-Cavestany, Wenjun Wang, Cynthia A Reinhart-King, Michael R King

Cell Death Dis. 2019 Nov 4;10(11):837.

PMID: 31685811

1

Chemical Activation of the Mechanotransduction Channel Piezo1

Ruhma Syeda, Jie Xu, Adrienne E Dubin, Bertrand Coste, Jayanti Mathur, Truc Huynh, Jason Matzen, Jianmin Lao, David C Tully, Ingo H Engels, H Michael Petrassi, Andrew M Schumacher, Mauricio Montal, Michael Bandell, etc.

Elife. 2015 May 22;4:e07369.

PMID: 26001275

1

Piezo1 Channel Activation Mimics High Glucose as a Stimulator of Insulin Release

Vijayalakshmi Deivasikamani, Savitha Dhayalan, Yilizila Abudushalamu, Romana Mughal, Asjad Visnagri, Kevin Cuthbertson, Jason L Scragg, Tim S Munsey, Hema Viswambharan, Katsuhiko Muraki, Richard Foster, etc.

Sci Rep. 2019 Nov 14;9(1):16876.

PMID: 31727906

1

Probing the Gating Mechanism of the Mechanosensitive Channel Piezo1 With the Small Molecule Yoda1

Jerome J Lacroix, Wesley M Botello-Smith, Yun Luo

Nat Commun. 2018 May 23;9(1):2029.

PMID: 29795280

1

Yoda1 Analogue (Dooku1) Which Antagonizes Yoda1-evoked Activation of Piezo1 and Aortic Relaxation

Elizabeth L Evans, Kevin Cuthbertson, Naima Endesh, Baptiste Rode, Nicola M Blythe, Adam J Hyman, Sally J Hall, Hannah J Gaunt, Melanie J Ludlow, Richard Foster, David J Beech

Br J Pharmacol. 2018 May;175(10):1744-1759.

PMID: 29498036

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