CAS 101975-10-4 Zardaverine - Analytical Products / Alfa Chemistry

CAT	AP101975104
CAS	101975-10-4
Structure
MDL Number	MFCD00867059
Molecular Weight	268.22
InChI Key	HJMQDJPMQIHLPB-UHFFFAOYSA-N; 2.5 μM IC50 (for PDE III)

Description	phosphodiesterase inhibitor
Size	5MG

1

A Dual Phosphodiesterase Inhibitor, Zardaverine (Type 3/4), Enhances Motility of Frozen-thawed Boar Sperm

J Jeong, S J Sa, H Chung, S Baek, I Choi

Cryo Letters. May/Jun 2018;39(3):196-200.

PMID: 30059566

1

Cytotoxicity of Zardaverine in Embryonal Rhabdomyosarcoma From a Costello Syndrome Patient

Donna M Cartledge, Katherine M Robbins, Katherine M Drake, Rachel Sternberg, Deborah L Stabley, Karen W Gripp, E Anders Kolb, Katia Sol-Church, Andrew D Napper

Front Oncol. 2017 Apr 3;7:42.

PMID: 28421158

1

Phosphodiesterase 3/4 Inhibitor Zardaverine Exhibits Potent and Selective Antitumor Activity Against Hepatocellular Carcinoma Both in Vitro and in Vivo Independently of Phosphodiesterase Inhibition

Liping Sun, Haitian Quan, Chengying Xie, Lei Wang, Youhong Hu, Liguang Lou

PLoS One. 2014 Mar 5;9(3):e90627.

PMID: 24598942

1

The Effect of Zardaverine, an Inhibitor of Phosphodiesterase Isoenzymes III and IV, on Endotoxin-Induced Airway Changes in Rats

J C Kips, G F Joos, R A Peleman, R A Pauwels

Clin Exp Allergy. 1993 Jun;23(6):518-23.

PMID: 8369979

1

Zardaverine and Aerosolised Iloprost in a Model of Acute Respiratory Failure

R T Schermuly, H Leuchte, H A Ghofrani, N Weissmann, F Rose, M Kohstall, H Olschewski, C Schudt, F Grimminger, W Seeger, D Walmrath

Eur Respir J. 2003 Aug;22(2):342-7.

PMID: 12952271

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