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Zatebradine hydrochloride

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For Research Use Only | Not For Clinical Use
CATAP91940873
CAS91940-87-3
Structure
MDL NumberMFCD06798356
Molecular Weight493.04
InChI KeyZRNKXJHEQKMWCH-UHFFFAOYSA-N
Description≥98% (HPLC), powder
SolubilityH2O: >10 mg/mL
Assay≥98% (HPLC)
Colorwhite
Formpowder
Size10MG, 50MG
Storage Conditions2-8°C
1

A Bradycardic Agent, UL-FS 49, Increases Atrial Force and Decreases Ventricular Force in Isolated, Perfused Heart Preparations of Dogs

Y Furukawa, S Takayama, S Sawaki, Y Inoue, S Chiba

J Pharmacol Exp Ther. 1993 May;265(2):801-6.

PMID: 8496825

1

Cardiovascular Characterization of UL-FS 49, 1,3,4,5-tetrahydro-7,8-dimethoxy-3-[3-][2-(3,4-dimethoxyphenyl)ethyl] methylimino]propyl]-2H-3-benzazepin-2-on Hydrochloride, a New "Specific Bradycardic Agent"

W Kobinger, C Lillie

Eur J Pharmacol. 1984 Sep 3;104(1-2):9-18.

PMID: 6499920

1

Comparative Effects of a Potassium Channel Blocking Drug, UK-68,798, and a Specific Bradycardic Agent, UL-FS 49, on Exercise-Induced Ischemia in the Dog: Significance of Diastolic Time on Ischemic Cardiac Function

B Gout, J Jean, A Bril

J Pharmacol Exp Ther. 1992 Sep;262(3):987-94.

PMID: 1527735

1

Investigations Into the Bradycardic Effects of UL-FS 49 (1,3,4,5-tetrahydro-7,8-dimethoxy-3-[3-[[2-(3,4-dimethoxyphenyl)ethyl] methylimino]propyl]-2H-3-benzazepin-2-on-hydrochloride) in Isolated Guinea Pig Atria

C Lillie, W Kobinger

J Cardiovasc Pharmacol. Jul-Aug 1986;8(4):791-7.

PMID: 2427820

1

Zatebradine: Pharmacokinetics of a Novel Heart-Rate-Lowering Agent After Intravenous Infusion and Oral Administration to Healthy Subjects

W Roth, E Bauer, G Heinzel, P J Cornelissen, R G van Tol, J H Jonkman, P B Zuiderwijk

J Pharm Sci. 1993 Jan;82(1):99-106.

PMID: 8429501

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