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ZLN005

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For Research Use Only | Not For Clinical Use
CATAP49671763
CAS49671-76-3
Molecular Weight250.34
Description≥95% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥95% (HPLC)
Colorwhite to beige
Formpowder
Size10MG, 50MG
Storage Conditions−20°C
1

BPDE and B[a]P Induce Mitochondrial Compromise by ROS-mediated Suppression of the SIRT1/TERT/PGC-1α Pathway in Spermatogenic Cells Both in Vitro and in Vivo

Wang Yang, Guowei Zhang, Fan Jiang, Yingfei Zeng, Peng Zou, Huihui An, Qing Chen, Xi Ling, Fei Han, Wenbin Liu, Huan Yang, Jinyi Liu, Jia Cao, Lin Ao

Toxicol Appl Pharmacol. 2019 Aug 1;376:17-37.

PMID: 31085209

1

Cisplatin Resistance Involves a Metabolic Reprogramming Through ROS and PGC-1α in NSCLC Which Can Be Overcome by OXPHOS Inhibition

Alberto Cruz-Bermúdez, Raquel Laza-Briviesca, Ramiro J Vicente-Blanco, Aránzazu García-Grande, Maria José Coronado, Sara Laine-Menéndez, Sara Palacios-Zambrano, M Rocío Moreno-Villa, Asunción Martin Ruiz-Valdepeñas, etc.

Free Radic Biol Med. 2019 May 1;135:167-181.

PMID: 30880247

1

In Vitro and in Vivo Metabolite Identification of a Novel Benzimidazole Compound ZLN005 by LC-MS/MS

Wenchao Sun, Khoa Dinh Nguyen, William L Fitch, Samuel D Banister, Hongxiang Tang, Xiaolan Zhang, Lewis Yu, Edgar G Engleman, Jayakumar Rajadas

Rapid Commun Mass Spectrom. 2018 Jan 15.

PMID: 29334584

1

Pharmaceutical Induction of PGC-1 α Promotes Retinal Pigment Epithelial Cell Metabolism and Protects against Oxidative Damage

Sangeeta Satish, Hannah Philipose, Mariana Aparecida Brunini Rosales, Magali Saint-Geniez

Oxid Med Cell Longev. 2018 Nov 5;2018:9248640.

PMID: 30524663

1

The PGC-1α Activator ZLN005 Ameliorates Ischemia-Induced Neuronal Injury In Vitro and In Vivo

Yazhou Xu, John Alimamy Kabba, Wenchen Ruan, Yunjie Wang, Shunyi Zhao, Xiaoyue Song, Luyong Zhang, Jia Li, Tao Pang

Cell Mol Neurobiol. 2018 May;38(4):929-939.

PMID: 29159732

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