Cinchonine and Thiourea

Yumeng Xi, Xiaodong Shi

Chem Commun (Camb). 2013 Oct 7;49(77):8583-5.

PMID: 23948716

Abstract:

In this viewpoint, we discuss the seminal work contributed by Dixon, who reported the first use of a bifunctional cinchona-derived thiourea organocatalyst for the enantioselective conjugate addition of malonate esters to nitroalkenes. Since then, this class of catalysts has been extensively utilized in a variety of fundamental transformations. We also highlight here some of the representative studies performed since the publication of this milestone work in 2005.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP118105	(+)-Cinchonine		118-10-5	Price