[13 Cases of Drug-Induced Calculi]

P Teillac, M Daudon, O de Dreuzy, H V Nguyen, R J Reveillaud, A Le Duc

Ann Urol (Paris). 1988;22(4):278-81.

PMID: 2903714

Abstract:

All urinary stones should undergo detailed studies to identify those related to drug therapy. Among 520 stones analyzed by infrared spectrophotometry, we found 13 drug-induced stones (13/520: 2.5%). Drug-induced stones were caused by glafenine in 7 cases, piridoxylate in 4 cases, triamterene in one case and an unknown organic compound in one case. Glafenine stones appear to develop more readily in infected urine. Triamterene stones are often associated with uric acid disorders. Piridoxylate induces the formation of glyoxylate which is responsible for hyperoxaluria and formation of oxalocalcium stones.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP1006231	Triamterene Related Compound A		1006-23-1	Price