nBu4NI-catalyzed Oxidative Imidation of Ketones With Imides: Synthesis of α-amino Ketones

Yunhe Lv, Yan Li, Tao Xiong, Yu Lu, Qun Liu, Qian Zhang

Chem Commun (Camb). 2014 Mar 4;50(18):2367-9.

PMID: 24448553

Abstract:

nBu4NI-Catalyzed oxidative imidation of ketones and imides for the synthesis of α-amino ketones were realized for the first time. The methodology is characterized by its wide substrate scope even for acetone with readily available phthalimide, saccharin and succinimide, which opens a new pathway for direct imidation of ketones.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP74830301	Tetrabutylammonium succinimide		74830-30-1	Price