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Proteomic Products

As an essential component of life science research, proteomics experiments heavily rely on high-quality experimental reagents, including protein standards, Western substrates, staining reagents, and more. Leveraging rich technical expertise and a stringent quality control system, Alfa Chemistry has developed a series of proteomics-specific products, widely used in various fields such as basic scientific research, biopharmaceuticals, and molecular diagnostics.

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Curious About Our Product Range?

In our collaborations with numerous clients, we have found that they often seek the following products, which have proven to be highly effective in meeting their needs and are widely popular.

Where Are Proteomic Reagents Applied?

Our proteomics reagents are widely applied in the following research and industrial fields:

  • Basic Life Science Research
  • Drug Development
  • Clinical Diagnosis
  • Precision Medicine

Basic Life Science Research

Proteomics reagents play a significant role in basic life sciences, primarily in the identification, functional analysis, and interaction studies of proteins. For example, through mass spectrometry and bioinformatics analysis, researchers can identify the type, abundance, and modification status of proteins, revealing their functions and regulatory mechanisms within the cell. Additionally, proteomics reagents are used to study post-translational modifications (PTMs) and their impact on protein activity, which is crucial for understanding protein function and regulation.

Drug Development

Proteomics reagents play a key role in drug development. Using proteomics technologies, researchers can screen potential drug targets, evaluate drug mechanisms of action, and optimize drug design. For instance, biomarker discovery based on proteomics can help identify disease-related protein expression changes, providing the foundation for early diagnosis and treatment. Moreover, proteomics reagents are used in drug screening and quality control to ensure the safety and efficacy of drugs.

Clinical Diagnosis

Proteomics reagents are applied in clinical diagnostics, including the development of diagnostic kits and companion diagnostic tools. With proteomics technologies, researchers can identify disease-related biomarkers that can be used for early disease screening, diagnosis, and prognosis evaluation. For example, antibody reagents, which are essential for protein modification analysis, can bind specific proteins and enrich target proteins, thereby enhancing the sensitivity and specificity of diagnostics.

Precision Medicine

Proteomics reagents in precision medicine are mainly applied in personalized healthcare and biomarker development. Through high-throughput proteomics analysis, researchers can perform personalized protein expression analysis for patients, enabling molecular subtyping of diseases and precise treatments. For instance, biomarker screening based on proteomics can help identify specific patient disease risks and treatment responses, providing scientific support for personalized treatment plans.

What Are Our Most Popular Products?

Here are some of our best-selling products. Click on the product name to view detailed information:

OneStep Blocker

Catalog Number: BS001-B500ML
Description: A fast and efficient Western blot blocking reagent, suitable for HRP and AP systems, designed to reduce nonspecific background.
Applications: WB, chemiluminescent imaging

UltraScence TMB ELISA Substrate

Catalog number: TM001-B100ML
Description: A highly sensitive TMB colorimetric substrate with strong color stability and clear signals.
Applications: ELISA detection, microplate colorimetric analysis

Why Choose Us?

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High Purity Products

We ensure experimental consistency and high sensitivity through multiple purification processes.

Strong Reproducibility

High batch-to-batch stability ensures reliable research data.

Complete Standards

We offer research-grade, analytical-grade, and mass spectrometry-grade products.

Custom Services

We provide formula optimization and custom packaging services.

Fast Delivery

Global Shipping: We maintain stock for quick dispatch and support various shipping options.

What Success Stories Can We Share?

Discover how our products are applied in real-world scenarios through our case studies.

Case 1: Application of IRIS9 Prestained Protein Ladder in Molecular Weight Determination for SDS-PAGE and Western Blot

Customer Background

A molecular biology laboratory focusing on viral structural protein expression and mutation analysis, routinely conducting a large number of SDS-PAGE and Western Blot experiments, frequently using molecular weight standards.

Application Need and Challenge

The research team required accurate molecular weight determination of recombinant viral capsid proteins, but the existing molecular weight markers had a single band color, making it difficult to identify after membrane transfer. This affected the accuracy of protein localization and comparison on the membrane.

Solution

The team selected our IRIS9 Prestained Protein Ladder, which contains 10 prestained bands covering a range of 10–180 kDa, with three differently color-coded reference bands, supporting the full process of SDS-PAGE and Western Blot experiments.

Experimental Results

  • Clear electrophoresis image with high contrast.
  • Bands remain clearly visible after membrane transfer.
  • Reference bands accurately match, aiding in precise identification of target proteins.
  • Post-experiment, the rework rate for electrophoresis decreased by approximately 42%, significantly improving experiment efficiency.

Case 2: Verification of the Advantage of UltraScence Pico Plus Western Substrate in Low-Abundance Signal Detection

Customer Background

A cancer research center studying the expression changes of low-abundance phosphorylated proteins in cancer progression. The target protein expression is extremely low, and conventional ECL substrates could not meet the detection requirements.

Application Challenge

Traditional chemiluminescent substrates lacked sufficient sensitivity, making it difficult to detect low-abundance target bands, especially under conditions with high background noise, leading to missed detections or false positives.

Solution

The team selected our high-sensitivity chemiluminescent substrate, UltraScence Pico Plus Western Substrate, suitable for HRP-labeled antibody systems, enabling the detection of proteins at the picomolar (pg) level.

Performance Verification

  • Experimental comparisons showed that after using Pico Plus, the signal intensity of the target band increased by 5.2 times.
  • Background signals were reduced by 43%, significantly improving the signal-to-noise ratio.
  • Stable chemiluminescence lasted for up to 6 hours, providing a more flexible imaging time window.
  • Successfully detected the expression changes of a 12 kDa phosphorylated protein, with results published in an SCI paper.

Case 3: Application of COOMASSIEnano Protein Staining Solution in Quantitative Analysis After Protein Electrophoresis

Customer Background

A biotechnology company's quality control department, required to regularly perform SDS-PAGE analysis on protein products and carry out sample normalization for quantification.

Pain Points with the Original Method

  • Traditional Coomassie staining required a long staining time (>3 hours).
  • High background, requiring a decolorization step, which was time-consuming and affected image quality.
  • Poor compatibility with subsequent LC-MS analysis.

Application Solution

The team adopted our ready-to-use, environmentally friendly COOMASSIEnano Protein Staining Solution, which does not require heating or decolorization, providing a convenient and efficient solution.

Experimental Performance

  • Staining completion time<20 minutes, reducing the total process time by over 60%.
  • Extremely low background after staining, improving image quality and facilitating software quantification.
  • Compared to silver staining, the method demonstrated higher reproducibility and is more suitable for batch analysis of multiple samples.
  • Verified by MALDI-TOF MS, the dye showed no interference with mass spectrometry analysis, exhibiting excellent compatibility.

What Our Clients Say?

"We purchased the IRIS9 Prestained Protein Ladder provided by your company for SDS-PAGE and Western Blot experiments. The pre-stained bands of this product are vividly colored and accurately positioned, which greatly improved the efficiency of our experiments. During the experiments, whether it was protein transfer or image capture, the bands were very clear, helping us to identify the target proteins more precisely. We are extremely satisfied with the performance of this product and will continue to purchase it in the future."

Avery Johnson, Laboratory Director, Molecular Biology Institute

"We recently purchased the UltraScence Pico Plus Western Substrate for detecting low-abundance protein expression. The sensitivity of this product far exceeds that of the substrates we used before, allowing detection of proteins at the picomolar level, with very low background noise. After use, the results were clear, and the signal intensity was sufficient, significantly enhancing the reproducibility and accuracy of our research. Highly recommended!"

Jordan Miller, Researcher, Cancer Research Center

"We used the COOMASSIEnano Protein Staining Solution for SDS-PAGE protein staining. This staining solution not only allows for quick staining but also has very low background, eliminating the need for additional destaining steps. It is convenient and efficient to use. The staining results were clear, and it did not interfere with our LC-MS analysis, greatly improving the efficiency of our experiments. Definitely recommend!"

Taylor Brooks, R&D Manager, Biopharmaceutical Company

"We purchased your company's Protein Marker/Ladder series products, including both pre-stained and non-stained markers. Whether used for protein electrophoresis or Western Blot experiments, the contrast of the marker bands is very high, the operation is simple, and the results are reliable. We are pleased to have found a product that meets our quality requirements and reduces experimental error. We will continue to choose your products in the future."

Morgan Davis, Researcher, Immunology Laboratory

"As a long-term researcher in proteomics, we chose your company’s Western Substrate products, particularly the chemiluminescent substrate. After use, the signals obtained in our experiments were very clear and lasted for a long time, greatly facilitating our image analysis. The product's performance is stable, significantly enhancing the quality and reliability of our experimental data. We sincerely appreciate the high-quality products provided by your company."

Alex Carter, Researcher, Basic Medical Research Institute

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