Biotransformation of (1S)-2-carene and (1S)-3-carene by Picea Abies Suspension Culture

Marcela Dvorakova, Irena Valterova, David Saman, Tomas Vanek

Molecules. 2011 Dec 19;16(12):10541-55.

PMID: 22183881

Abstract:

Biotransformation of (1S)-2-carene and (1S)-3-carene by Picea abies suspension culture led to the formation of oxygenated products. (1S)-2-Carene was transformed slowly and the final product was identified as (1S)-2-caren-4-one. On the other hand, the transformation of (1S)-3-carene was rapid and finally led to the formation of (1S)-3-caren-5-one and (1S)-2-caren-4-one as equally abundant major products. The time-course of the reaction indicates that some products abundant at the beginning of the reaction (e.g. (1S, 3S, 4R)-3,4-epoxycarane and (1R)-p-mentha-1(7),2-dien-8-ol) were consumed by a subsequent transformations. Thus, a precise selection of the biotransformation time may be used for a production of specific compounds.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP498157-A	(+)-3-Carene		498-15-7	Price
AP1219810168	1S,3R-RSL 3		1219810-16-8	Price