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UV blockers are chemicals added to cosmetics that absorb most of the ultraviolet rays and act as skin protectors. However, excessive addition of UV blockers in cosmetics will stimulate the skin, causing rashes, skin inflammation, blackening and others. Therefore, in order to ensure the quality and safety of cosmetics, many countries and organizations have strictly restricted on the type and content of UV blockers. Furthermore, in UV blockers analysis, standard substances are required, which can be either a single chemical or a mixture of many chemicals. Commonly used UV blockers standards include benzophenone-9, ethyl cinnamate, ethylhexyl triazone, dioxybenzone, benzylidene camphor sulfonic acid, 4-aminobenzoic acid, ethyl cinnamate and others.
Analysis of UV blockers by high performance liquid chromatography: UV blockers standards are widely used in high performance liquid chromatography to achieve quantitative or qualitative analysis of UV blockers. In general, the standards solution is prepared by diluting the UV blockers standards with methanol solvent, which is necessary to obtain the standard curves. Based on the characteristic that the content of detected UV blockers is proportional to the peak strength or peak area, the quantitative detection of UV blockers can be realized. For example, it has been reported that nine types of UV blockers can be detected in cosmetics using mixed standard solutions.
Analysis of UV blockers by reversed-phase high-performance liquid chromatography: The quantitative and qualitative analysis of UV blockers by reversed-phase high-performance liquid chromatography is inseparable from the analysis of UV blockers substances. Compared with other methods, reversed-phase high-performance liquid chromatography has the advantages of high sensitivity, fast analysis speed and simplicity. For example, 4-p-aminobenzoic acid, butyl methoxydiphenylmethane, hydroxybenzoate and other UV blocker components can be detected by RP-HPLC method, indicating that this method is very practical.
Others: In addition to the fields mentioned above, UV blocker standards are also widely used in other fields, including liquid chromatography-mass spectrometry, gas chromatography-mass spectrometry, ultra-high liquid chromatography and others. Liquid chromatography-mass spectrometry is an analytical chemical technique that combines the physical separation capability of high-performance liquid chromatography with the quality analysis capability of mass spectrometry. In addition, gas chromatography-mass spectrometry is an analytical chemical technique that combines the physical separation capability of gas chromatography with the quality analysis capability of mass spectrometry. Ultra-high liquid chromatography has the same principle as liquid chromatography, but it has higher sensitivity. These methods are common in UV blockers analysis and UV blocker standards are essential.
Alfa Chemistry is one of the largest providers of UV blockers in the world and the quality assurance is of prime importance to Alfa Chemistry. The solvent from Alfa Chemistry in the world is synonymous with reliability and excellent quality. Because of the exacting nature of our business and the regulatory demands placed upon our industry, Alfa Chemistry continues to be at the forefront in terms of compliance, accreditations and certifications.