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In the field of life sciences, pathway metabolites are produced in metabolic reactions of the organisms. The changes in the content and types of pathway metabolites can reflect the life activities of living organisms, which can be used to judge the health of the living organisms. Substances that play important roles in the production of pathway metabolites include acetyl coenzyme A, oxaloacetic acid, glucose hexaphosphate, glutamic acid and others. Therefore, it is of great significance to accurately analyze those substances for life science researches.
Among many detection methods, the quantitative or qualitative analysis of metabolites by chromatography is an efficient method, which is on the base of pathway metabolites standards. The pathway metabolites standards are physical standards which have one or more eigenvalues. Furthermore, the eigenvalues of pathway metabolites standards have certain confidence.
Diagnosis of disease: In the life sciences, the primary use of pathway metabolites standards is to diagnose diseases. Using pathway metabolites standards, analyzing the types and contents of pathway metabolites in biological samples can basically play an auxiliary role in diagnosis. For example, it has been reported that the occurrence of atherosclerosis is closely related to the metabolic reactions involved by coenzyme A. After proper pretreatment of biological samples, differences between the detected samples and normal biological samples can be distinguished by comparison with pathway metabolites standards. Therefore, it can provide data support for the diagnosis of atherosclerosis.
Others: Pathway metabolites standards can also be used to analyze the life activity of bacteria or fungi, which can be used to determine the species of bacteria or fungi. In addition, in the industry that needs fermentation, the use of pathway metabolites standards to detect the metabolites of microorganisms can realize the control of products quality.
Alfa Chemistry is one of the largest providers of pathway metabolites for chromatography in the world and the quality assurance is of prime importance to Alfa Chemistry. The solvent from Alfa Chemistry in the world is synonymous with reliability and excellent quality. Because of the exacting nature of our business and the regulatory demands placed upon our industry, Alfa Chemistry continues to be at the forefront in terms of compliance, accreditations and certifications.