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In the field of pharmaceutical, water soluble polymer materials are widely used, which can be used in pharmaceutical excipients, pharmaceutical packaging, medical materials and other aspects. Analysis of the physical and chemical properties of water soluble polymer materials used in the pharmaceutical process plays an important role in the safety and quality of drugs. Water soluble polymers analytical standard is a branch of the reference materials. In addition, water soluble polymers analytical standards have one or more characteristic values, which can be used to calibrate measuring instruments and devices, evaluate measurement and analysis methods, assess the operating skills of analysts, and control product quality.
Generally, the water soluble polymers analytical standards are powders or crystals. Furthermore, according to the analysis needs, appropriate solvents can be selected to dilute the water soluble polymers analytical standards into the standard solution with required concentration. Commonly used water soluble polymers analytical standards include dextran, poly (acrylic acid sodium salt), poly (ethylene glycol), pullulan and others.
Gel permeation chromatography (GPC): Water soluble polymers analytical standards are widely used in gel permeation chromatography. In the test process, the water soluble polymers analytical standards are used to make a curve in advance of the elution volume or elution time and the relative molecular weight. This line is called the correction curve, which is the basis of the subsequent analysis and test. For example, dextran is a sticky substance like starch and dextrin produced by microorganisms, which can be used as a blood volume extender drug. The molecular weight and molecular weight distribution of dextran can be determined by high performance gel penetration chromatography (HPGPC) based on the calibration curves of water soluble polymers analytical standards.
Alfa Chemistry is one of the largest providers of water soluble polymers analytical standards in the world and the quality assurance is of prime importance to Alfa Chemistry. The solvent from Alfa Chemistry in the world is synonymous with reliability and excellent quality. Because of the exacting nature of our business and the regulatory demands placed upon our industry, Alfa Chemistry continues to be at the forefront in terms of compliance, accreditations and certifications.