Endogenous Metabolites Standards

Endogenous Metabolites Standards

Endogenous metabolites testing is a new technology to study all metabolic pathways in organisms by studying the changes of metabolites after stimulation or disturbance, which is modeled on the research ideas of genomics, transcriptomics and proteomics. The study subjects of endogenous metabolites testing are mainly endogenous small molecules with a relative molecular weight of less than 1000. Compared with other analytical methods, endogenous metabolites testing can reflect the physiological and pathological state of the body system more truly, and provide an instantaneous and comprehensive snapshot for the ongoing biological process.

Due to the active enzyme system and rapid metabolic transformation in cells, sampling and sample preparation methods significantly affect the accuracy and repeatability of analysis results. Therefore, establishing analytical standards for sampling and sample preparation methods of endogenous metabolites testing is important. However, according to the research objects, purposes and analysis techniques, the pretreatment requirements of samples are also inconsistent, and there are no analytical standards so far. In the process of samples pretreatments, the regents used are mainly methanol, sodium chloride, perchloric acid, acetonitrile, isopropyl alcohol and others.

Application fields

Generally, the steps of sample treatment can be divided into cell quenching and metabolite extraction.

Why choose Alfa Chemistry?

Alfa Chemistry is one of the largest providers of analytical standards for endogenous metabolites testing in the world and the quality assurance is of prime importance to Alfa Chemistry. The solvent from Alfa Chemistry in the world is synonymous with reliability and excellent quality. Because of the exacting nature of our business and the regulatory demands placed upon our industry, Alfa Chemistry continues to be at the forefront in terms of compliance, accreditations and certifications.

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