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Hypotension in the Horse Induced by Acepromazine Maleate

Hypotension in the Horse Induced by Acepromazine Maleate

B W Parry, G A Anderson, C C Gay

Aust Vet J. 1982 Nov;59(5):148-52.

PMID: 6131662

Abstract:

The hypotensive effect of acepromazine maleate was related to both the dose and route of administration. The degree and duration of hypotension varied between individual horses. In general, intravenous administration produced a more rapid maximum effect than intramuscular injection and the larger the dose the longer blood pressure remained at low levels. Average systolic pressure (of 6 horses) remained significantly below control values for more than 6 h after an intramuscular injection of 0.05 mg acepromazine maleate/kg body weight. Respiratory rate was markedly decreased, with the duration, but not the degree of bradypnoea related to the dose administered. A slight, transient decrease in body temperature was observed. Heart rate was not significantly influenced by administration of acepromazine maleate.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP3598376-A	Acepromazine maleate		3598-37-6	Price

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