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Thickened Infant Formula: What to Know

Thickened Infant Formula: What to Know

Silvia Salvatore, Francesco Savino, Maartje Singendonk, Merit Tabbers, Marc A Benninga, Annamaria Staiano, Yvan Vandenplas

Nutrition. 2018 May;49:51-56.

PMID: 29495000

Abstract:

Objectives:
This study aimed to provide an overview of the characteristics of thickened formulas to aid health care providers manage infants with regurgitations.
Methods:
The indications, properties, and efficacy of different thickening agents and thickened formulas on regurgitation and gastroesophageal reflux in infants were reviewed. PubMed and the Cochrane database were searched up to December 2016.
Results:
Based on the literature review, thickened formulas reduce regurgitation, may improve reflux-associated symptoms, and increase weight gain. However, clinical efficacy is related to the characteristics of the formula and of the infant. Commercial thickened formulas are preferred over the supplementation of standard formulas with thickener because of the better viscosity, digestibility, and nutritional balance. Rice and corn starch, carob bean gum, and soy bean polysaccharides are available as thickening agents. Hydrolyzed formulas have recently shown promising additional benefit.
Conclusions:
Thickened formulas reduce the frequency and severity of regurgitation and are indicated in formula-fed infants with persisting symptoms despite reassurance and appropriate feeding volume intake.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AS2121041	Medical Viscosity Standard			Price

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