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Devil's Claw (Harpagophytum Procumbens) and Chronic Inflammatory Diseases: A Concise Overview on Preclinical and Clinical Data

Luigi Menghini, Lucia Recinella, Sheila Leone, Annalisa Chiavaroli, Carla Cicala, Luigi Brunetti, Sanda Vladimir-Knežević, Giustino Orlando, Claudio Ferrante

Phytother Res. 2019 Sep;33(9):2152-2162.

PMID: 31273865

Abstract:

Devil's Claw is a traditional medicine that has been long used a wide range of health conditions, including indigestion, fever, allergic reactions, and rheumatism. The main compounds are iridoid glycosides, including harpagoside, harpagide, and procumbide. However, harpagoside is the most responsible for therapeutic activity, and its content is used as reference standard. Here, we analyzed and summarized preclinical and clinical studies focusing on therapeutic efficacy of devil's claw preparations in pathological conditions in which inflammation plays a key causative role.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP6926085 Harpagide Harpagide 6926-08-5 Price
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