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The Conversion of cholest-5-en-3beta-ol Into cholest-7-en-3beta-ol by the Echinoderms Asterias Rubens and Solaster Papposus

A G Smith, L J Goad

Biochem J. 1975 Jan;146(1):35-40.

PMID: 1147903

Abstract:

1. The echinoderms Asterias rubens and Solaster papposus (Class Asteroidea) metabolize injected [4(-14)C]cholest-5-en-3beta-ol to produce labelled 5alpha-cholestan-3beta-ol and 5alpha-cholest-7-en-3beta-ol. 2. Conversion of 5alpha-[4(-14)C]cholestan-3beta-ol into 5alpha-cholest-7-en-3beta-ol was demonstrated in A. Rubens. 3. Incubations of A. rubens with [4(-14)C]cholest-4-en-3-one resulted in the production of labelled 5alpha-cholestan-3-one, 5alpha-cholestan-3beta-ol and 5alpha-cholest-7-en-3beta-ol. 4. [4(-14)C]Sitosterol was metabolized by A. rubens to give 5alpha-stigmastan-3beta-ol and 5alpha-stigmast-7-en-3beta-ol. 5. The significance of these results in relation to the presence of alpha7 sterols in starfish is discussed.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP80999 5α-Cholest-7-en-3β-ol 5α-Cholest-7-en-3β-ol 80-99-9 Price
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