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1-Phenylisoquinoline Larvicidal Activity Against Culex Quinquefasciatus

Rodolfo Quevedo, Edwin Baquero, Martha L Quiñones

Nat Prod Res. 2012;26(12):1094-100.

PMID: 22044222

Abstract:

The larvicidal potential of several dopamine 1-phenylisoquinoline derivatives against Culex quinquefasciatus third instar larvae was investigated in a rational search for insecticides. The results showed that these isoquinolines presented moderate larvicidal activity, that the presence of a substituent is needed on carbon 1 for such activity to be presented and that it may be possible to develop novel insecticidal compounds having potential use in controlling insects by appropriate structural modification of 1-phenylisoquinolines. This article presents a possible structure-larvicidal activity relationship for isoquinolinic compounds.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP3297721 1-Phenylisoquinoline 1-Phenylisoquinoline 3297-72-1 Price
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