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6-Methylcoumarin Photocontact Dermatitis

R T Jackson, L T Nesbitt Jr, V A DeLeo

J Am Acad Dermatol. 1980 Feb;2(2):124-7.

PMID: 7364969

Abstract:

Sporadic cases of a severe photocontact dermatitis have appeared in the last few years following use of fruity-smelling suntan preparations and sunlight exposure. We report five such cases in women who developed severe edema and erythema of sun-exposed areas shortly after application of agents containing 6-methylcoumarin used as fragance. Routine photopatch testing was unproductive in reproducing the reaction, but immediate application of 6-methylcoumarin before ultraviolet A (UVA) radiation elicited significant positive results.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP92488 6-Methylcoumarin 6-Methylcoumarin 92-48-8 Price
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