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A Bovine Glucuronidase for Assembly of beta-D-glucuronyl-(1-3)-6-O-sulfo-beta-D-gluco- And Galacto-Pyranosyl Linkages

A Bovine Glucuronidase for Assembly of beta-D-glucuronyl-(1-3)-6-O-sulfo-beta-D-gluco- And Galacto-Pyranosyl Linkages

Hirotaka Uzawa, Takehiro Nagatsuka, Hideo Hiramatsu, Yoshihiro Nishida

Chem Commun (Camb). 2006 Apr 7;(13):1381-3.

PMID: 16550273

Abstract:

Glucuronidase-catalyzed transglycosylation was examined by using 4-nitrophenyl beta-D-glucuronide (D-GlcA-O-pNP) as the glycosyl donor; when pNP 6-O-sulfo-beta-D-gluco- and D-galacto-pyranosides were used as the acceptors, a bovine enzyme was found to construct beta-D-GlcA-(1-3)-linkages with the 6-O-sulfo-sugars in both a site- and beta-selective way.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP10344942	4-Nitrophenyl β-D-glucuronide		10344-94-2	Price

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