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A Comparative Study of the Permeation of Dihexadecyl Phosphate Vesicles by Various Carboxylic Acids and Some of Their Tetrazole Analogues

A Comparative Study of the Permeation of Dihexadecyl Phosphate Vesicles by Various Carboxylic Acids and Some of Their Tetrazole Analogues

P Pernice, M Castaing, P Ménassa, J L Kraus

Biophys Chem. 1988 Oct;32(1):15-20.

PMID: 3233310

Abstract:

The evaluation of the effect that perturbers may have on a membrane model is described. The model was made from dihexadecyl phosphate bilayers. The perturbers used were carboxylic acids and some of their tetrazole analogues. The results show a good correlation between the permeation properties of the carboxylic acids and tetrazole analogues. Moreover, this study reveals that membrane-perturbing effects are mainly under the control of conformational parameters and dependent on the carbon chain length of the permeants.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP2197639	Dihexadecyl phosphate		2197-63-9	Price

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