Home
Resources
Publications
A Disposable, Reagentless, Third-Generation Glucose Biosensor Based on Overoxidized poly(pyrrole)/tetrathiafulvalene-tetracyanoquinodimethane Composite

A Disposable, Reagentless, Third-Generation Glucose Biosensor Based on Overoxidized poly(pyrrole)/tetrathiafulvalene-tetracyanoquinodimethane Composite

Francesco Palmisano, Pier Giorgio Zambonin, Diego Centonze, Maurizio Quinto

Anal Chem. 2002 Dec 1;74(23):5913-8.

PMID: 12498183

Abstract:

A disposable glucose biosensor based on glucose oxidase immobilized on tetrathiafulvalene-tetracyanoquinodimethane (ITF-TCNQ) conducting organic salt synthesized in situ onto an overoxidized poly(pyrrole) (PPy(ox).) film is described. The TIF-TCNQ crystals grow through the nonconducting polypyrrole film (ensuring electrical connection to the underlying Pt electrode) and emerge from the film forming a treelike structure. The PPy(ox) film prevents the interfering substances from reaching the electrode surface. The sensor behavior can be modeled by assuming a direct reoxidation of the enzyme at the surface of the TTF-TCNQ crystals. A heterogeneous rate constant around 10(-6) - 10(-7) cm s(-1) has been estimated. The biosensor is nearly oxygen- and interference-free and when integrated in a flow injection system displays a remarkable sensitivity (70 nA/mM) and stability.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP40210842	Tetrathiafulvalene 7,7,8,8-tetracyanoquinodimethane salt		40210-84-2	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: