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A facile hydrothermal synthesis of highly luminescent NaYF 4:Yb 3+/Er 3+ upconversion nanoparticles and their biomonitoring capability

Rafia Rafique, Seung Hoon Baek, Le Minh Tu Phan, Sung-Jin Chang, Anam Rana Gul, Tae Jung Park

Mater Sci Eng C Mater Biol Appl. 2019 Jun;99:1067-1074.

PMID: 30889639

Abstract:

Using a facile hydrothermal procedure, hydrophilic NaYF4: Yb3+/Er3+ nanoparticles (NPs) have been prepared as lanthanide-doped upconversion (UC) materials exhibiting different morphologies, crystal phases and luminescence intensity. The upconversion nanoparticles (UCNP) were characterized by means of electron microscopy and spectroscopy, X-ray diffraction (XRD) and photoluminescence analysis. The molar concentration of reactants and volumes of NaF affect the shapes and uniformity of the synthesized NPs. These parameters also have influence on crystal phase and luminescence intensity of the NPs. Adjusting hydrothermal reaction time and dopant concentration also enable the synthesis of NPs with strong UC luminescence. The as-prepared UCNP showed cellular nontoxicity to HeLa cells, and thus they are capable as promising agents for biological imaging.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
LS71332 Sodium yttrium fluoride, ytterbium and erbium doped Sodium yttrium fluoride, ytterbium and erbium doped Price
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