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[A New Benzophenone Isolated From Fibrous Roots of Anemarrhena Asphodeloides]

[A New Benzophenone Isolated From Fibrous Roots of Anemarrhena Asphodeloides]

Zhen-Dong Liao, Feng-Qing Xu, De-Ling Wu, Wei Zhang, Qi Huang

Zhongguo Zhong Yao Za Zhi. 2019 Apr;44(7):1392-1396.

PMID: 31090296

Abstract:

Five compounds were isolated from the fibrous roots of Anemarrhena asphodeloides by silica gel, Sephadex LH-20 and semi-HPLC column chromatography. On the basis of physic-chemical properties and spectroscopic data analysis, these compounds were identified as methyl 2-[2,4-dihydroxy-3-(4-hydroxybenzoyl)-6-methoxyphenyl]acetate(1), 4-[formyl-5-(methoxymethyl)-1H-pyrrol-1-yl]butanoate(2), perlolyrine(3),syringaresinol-4'-O-β-D-glucoside(4) and 4',6-dihydroxy-4-methoxybenzophenone-2-O-(2″),3-C-(1″)-1″-desoxy-α-L-fructofuranoside(5). Among them, 1 was a new benzophenone. Compounds 2-5 were isolated from this plant for the first time. Compound 1 was tested for neuroprotective effects against H_2O_2-induced damage in SH-SY5 Y cells.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP137038132	(−)-Syringaresinol 4-O-β-D-glucoside		137038-13-2	Price

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