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A New Inhibitor of Protein Kinase C, RK-1409 (7-oxostaurosporine). II. Fermentation, Isolation, Physico-Chemical Properties and Structure

H Koshino, H Osada, K Isono

J Antibiot (Tokyo). 1992 Feb;45(2):195-8.

PMID: 1556010

Abstract:

RK-1409, a new inhibitor of protein kinase C, was isolated from the culture broth of Streptomyces platensis subsp. malvinus RK-1409. The structure was elucidated as 7-oxostaurosporine on the basis of spectroscopic analyses and oxidation of staurosporine.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP125035838 7-Oxostaurosporine 7-Oxostaurosporine 125035-83-8 Price
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