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A Palladium-Catalyzed Tandem Reaction of 2-(2-bromobenzylidene)cyclobutanone With 2-alkynylphenol

Xiaolin Pan, Yong Luo, Hong-Guang Xia, Jie Wu

Chem Commun (Camb). 2015 Nov 28;51(92):16483-5.

PMID: 26414750

Abstract:

An efficient approach for the generation of benzo[b]naphtho[2,3-d]oxocin-6-ones through a palladium-catalyzed tandem reaction of 2-alkynylphenol with 2-(2-bromobenzylidene)cyclobutanone is described. This tandem process afforded the fused polycycles easily, with the formation of three bonds with high efficiency, starting from easily available materials. Good functional group tolerance as well as excellent selectivity was displayed.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AS24722 2-(Tetradecyl-d29)cyclobutanone 2-(Tetradecyl-d29)cyclobutanone Price
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